The National Center for Advancing Translational Sciences (NCATS), is seeking a Senior Scientist to serve as the Director of the Early Translation Branch (ETB), Division of Pre-Clinical Innovation (DPI). The ETB Director is responsible for planning and directing a comprehensive program in the discovery of pharmacological tools to probe the function of the human genome and to understand and improve the processes underlying early discovery.

Duties

The ETB Director is responsible for planning and directing a comprehensive program in the discovery of pharmacological tools to probe the function of the human genome and to understand and improve the processes underlying early discovery. Research areas include the discovery of probe molecules to interrogate biology and de-risk disease hypotheses, using approaches such as high-throughput screening and computational methods, developing innovative methods for assaying the biological activity of novel gene targets and pathways, with a commitment to an open approach to sharing methodologies and data. ETB leverages state-of-the-art discovery resources - including robotic high-throughput screening facilities, compound management, and analytical chemistry - to deliver on this mission. This position will serve as a senior leader for the science and administration of this large and complex early translation program and serve as the spokesperson for the Branch at conferences and various stakeholder meetings, both nationally and internationally. In consultation with the NCATS Scientific Director (SD), the position is responsible for managing the research portfolio of ETB, ensuring ETB adapts to shifting discovery paradigms where necessary to remain state-of-the-art in its field, and enabling effective partnerships with other programs within DPI and NCATS. In partnership with the NCATS SD, the position is responsible for establishing the goals and objectives for the ETB, ensuring alignment with the goals and objectives determined at higher levels within the Center, and managing a collaborative portfolio of preclinical projects. The position is also responsible for developing long and short-range plans and establishing priorities, determining the resources required to support planned activities, and developing and defending annual budgets for the program.

Requirements

• U.S. Citizenship requirement or proof of being a U.S. National must be met by closing date.
• Employment is subject to the successful completion of a background investigation, verification of qualifications, completion of onboarding forms, submission of required documents, and any other job-related requirement before or after appointment.
• Applicants must meet all qualification requirements by the closing date of this announcement.
• Males born after December 31, 1959 must be registered with the Selective Service.
• Position requires Education. Please provide transcripts.

Qualifications

In order to qualify for a Supervisory Biochemist, GS-0401-15 position you must meet the following requirements: BASIC QUALIFICATIONS: A. have completed the requirements for a bachelor's degree in a biological science, agriculture, natural resource management, chemistry, or related disciplines appropriate to this position, from an accredited college or university; OR B. have a combination of experience and education which includes courses comparable to a major in a biological science, agriculture, natural resource management, chemistry or related disciplines appropriate to this position, AND have appropriate experience or additional education which demonstrates similarly appropriate skills or abilities needed to perform the duties of this position. ADDITIONAL QUALIFICATIONS: In addition to meeting the education requirements, you must demonstrate in your resume at least one (1) year of qualifying experience equivalent to at least the GS-14 level in the Federal service obtained in either the private or public sector, performing the following types of tasks: directing and managing a large scientifically diverse research program in comprehensive early translational science; working in a multi-disciplinary research environment related to the pre-clinical development of various therapeutic modalities; consolidating research information to generate new strategies and approaches in collaboration with other scientists; overseeing therapeutic development of rare diseases, including small molecule, biologic, and gene therapy approaches; and accomplishing early discovery through the pre-clinical development of therapeutics and diagnostics to proof- of -concept in humans. IDEAL CANDIDATE: Strong background in biomedical sciences as well as a record of accomplishment in academic and/or biopharmaceutical pre-clinical translation, with demonstrated experience leading multidisciplinary research groups in technology and therapeutic/diagnostic/intervention discovery. High-level expertise in planning and directing a comprehensive program in early translational science, from target validation through the discovery of pharmacological tools to probe the function of the human genome. Proven ability to creatively approach and solve complex technical problems in the preclinical development space. Extensive research training and experience in academia, the biopharmaceutical industry, and/or the government. Recognized nationally and internationally for scientific leadership. Expertise and accomplishment in multiple aspects of preclinical translation from early discovery through the preclinical development of therapeutics and/or diagnostics to proof-of-concept in humans. Has broad and first-hand knowledge of the field of rare disease therapeutic development, including small molecule, biologic, and gene-therapy approaches. Evidence of commitment to Diversity, Equity, Inclusion, and Accessibility (DEIA) To determine your qualifications and referral status, we may review your resume and supporting documentation and compare it against your responses to the vacancy questionnaire. Ensure you support your self-ratings with the information you provide in your application. We may verify or assess your qualifications at any time. Inflated or unsupported qualifications may affect your rating. Any misrepresentation or material omission of facts may be sufficient cause to end further consideration of your candidacy. Persons listed as knowing your past accomplishments or experience in your application may be contacted for verification purposes at any time. Verification may, but need not, begin before receiving an offer. You will receive credit for all experience material to the position, including experience gained in religious, civic, welfare, service, and organizational activities, regardless of whether you received pay. Do not copy and paste the duties, specialized experience, or occupational assessment questionnaire from this announcement into your resume as that will not be considered a demonstration of your qualifications for this position. Preview assessment questionnaire before you apply: https://apply.usastaffing.gov/ViewQuestionnaire/12533093

Education

This position has an education requirement. You are strongly encouraged to submit a copy of your transcripts (or a list of your courses including titles, credit hours completed and grades). Unofficial transcripts will be accepted in the application package. Official transcripts will be required from all selectees prior to receiving an official offer. Click here for information on Foreign Education.

Contacts

• Address National Institutes of Health 6701 Rockledge Drive Bethesda, MD 20892 US
• Name: Synthia Barnette
• Email: [email protected]